Back in 2003, Cartoon Network made downloadable games available for their website, under the name, "Cartoon Network Powerplay," which could be purchased or download for free for a limited time, similar to Nickelodeon's competing "Nick Arcade." One of the downloadable games was "Bowl-Ed Over," which was an Ed, Edd n Eddy themed game. It had multiplayer for up to 4 players and full-screen support.
The description on the website states,
"Bowling goes 3-D! Customize your own ball, then let the good times roll as the Eds cheer you on. Pump up the pin action on two Ed-built alleys: the Bowl-de-Sac and Kanker Lane. You can practice on your own, or challenge up to three other players!"
There is a download link, but when you try to click "Play Now", it won't respond. https://web.archive.org/web/20040715040644/http://i.cartoonnetwork.com/toon/powerplay/games/bowled_over/BowlEdSetup.exe
The only images you can see are the ones on the website. https://web.archive.org/web/20040605095824/http://www.cartoonnetwork.com/powerplay/games/bowled_over/
It has a strange resemblance to another game called "Gutterball Bowling."
Update, December 17, 2018 - TOMYSSHADOW found the demo, and you can download it here: